What to expect when starting your clearer skin journey

With ABSORICA LD (pronounced AB-SORE-I-KAH EL-DEE), there’s a lot you could look forward to—like finally getting the chance to show the world the true you. First, there are a few things you’ll need to know before starting your journey toward clearer skin.


What to expect with ABSORICA LD

ABSORICA LD works to reduce persistent severe (nodular) acne. Some patients may see improvements within the first month. ABSORICA LD works differently for everyone. Results could happen quickly, or it could take 5 months to see visibly clearer skin.

When first starting ABSORICA LD, some people may experience acne flare-ups, while others may start to see their skin clear up. Flare-ups can sometimes happen during treatment but shouldn’t last long. What someone else experiences could be different from what you experience.

Skin dryness may occur during your treatment. There are things you can use to help—like lip balms and moisturizers, which are provided in the ABSORICA LD welcome kit to help you manage these symptoms.

You could achieve complete and lasting remission in 5 months. Once treatment is completed, some people may continue to see their skin clear up. ABSORICA LD may even help prevent the development of new acne.

Record your personal journey to clearer skin

You may feel that your persistent severe (nodular) acne is all that people see. But you could have a chance to reveal the real you. With the downloadable journal, you can keep track of your experience with persistent severe (nodular) acne and get tips from dermatologists who have treated patients like you.

Sign Up

How to take ABSORICA LD

Your dermatologist can help to guide you in this journey toward clearer skin and will prescribe the most appropriate dosage for you. That’s why it’s important to take ABSORICA LD as prescribed. Here are some other things for you to consider while taking ABSORICA LD.

ABSORICA LD™ provides optimal absorption with or without food in 4 low-dose options

Uniquely LOW dosing
ABSORICA LD is the only isotretinoin that offers 4 low-dose options.

ABSORICA LD™ micronization technology

Micronization technology
ABSORICA LD features micronization technology that helps your body absorb the maximum amount of medication with less drug.

Absorption with or without food

With or without food
ABSORICA LD should be taken twice a day but does not have to be taken with meals for the maximum amount of absorption.


Miss it? Skip it
Be sure to take ABSORICA LD as prescribed. If you miss a dose though, just skip that dose.

Continuous results for persistent severe (nodular) acne

Move beyond the breakouts
ABSORICA LD should be taken for 15 to 20 weeks or as your dermatologist prescribes. After you stop treatment, keep in mind that your skin could continue to improve over time—even after treatment.

Ask for ABSORICA LD™ by name

Ask for ABSORICA LD by name
To get the only low-dose isotretinoin available, ask for ABSORICA LD (pronounced AB-SORE-I-KAH EL-DEE) by name at the pharmacy.

Be sure to discuss any medications you may be taking with your dermatologist, as well as any family history of mental illness.

You could receive ABSORICA LD at no cost*

ABSORICA LD is covered by the majority of commercial insurance plans. And you could pay $0 for your ABSORICA LD prescription with the ABSORICA LD Copay Card. If you don’t have commercial insurance, you may still be eligible to get your prescription at no cost to you through the Patient Assistance Program.

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*Eligibility limits apply. Click here to see full limits and conditions.

Encountering possible side effects

Just like with any medication, you could experience side effects while taking ABSORICA LD. Here are the side effects most often reported. The common questions section below can help answer any additional questions you may have throughout your treatment journey.

  • Acne flare-ups
  • Dryness
  • Sensitivity to sunlight
  • Acne flare-ups

    When you first start taking ABSORICA LD, you may notice a worsening of your acne. These flare-ups should only last a short while before your skin starts getting visibly clearer.

  • Dryness

    When taking ABSORICA LD, you may experience dryness of the eyes, lips, and/or skin. This is typical, as ABSORICA LD decreases oil production in order to help you achieve clearer skin. Moisturizers and lip balms can help soothe your dryness until this subsides. Ask your dermatologist about the ABSORICA LD welcome kit when you receive your prescription to get some of these helpful products at no cost to you.

  • Sensitivity to sunlight

    ABSORICA LD is a derivative of vitamin A, which can make your skin more sensitive to the sun. In order to protect your skin, you should be careful to avoid excessive sunlight and tanning beds. If you do spend time in the sun, be sure to apply sunscreen, wear a hat, or cover up with long sleeves and pants.

Other common side effects include back pain, joint or muscle pain, inflammation of the lips or skin, headaches, nosebleeds, common colds, upper respiratory tract infection, blurred eyesight, and increased blood creatine kinase.

If you experience any side effect that bothers you or does not go away, be sure to talk to your dermatologist.

Common questions about ABSORICA LD

Starting on a new medication can leave you with a number of questions. So, we’ve put together some frequently asked questions that patients sometimes have about ABSORICA LD. If you don’t see your question here, you can consult the Medication Guide or ask your dermatologist.

Paying for ABSORICA LD

Will my insurance cover ABSORICA LD?

The majority of commercial insurance plans cover ABSORICA LD. You can also sign up for the ABSORICA LD Copay Card to pay as little as $0 a month.*

Patients are not eligible if prescriptions are paid in part or full by any state- or federally funded programs, included but not limited to Medicare or Medicaid, Medigap, VA, DOD, or Tricare, and where prohibited by law.

What if my insurance does not cover ABSORICA LD?

If your insurance doesn’t cover your ABSORICA LD prescription, there are still options for you. The ABSORICA LD Patient Assistance Program (PAP) is available for uninsured and underinsured patients. If you qualify, you may be able to receive your medication at no cost to you.

What will my out-of-pocket costs be for ABSORICA LD?

Every insurance is different, but most patients can expect to pay an average of $50 for their prescription each month. To help cover these costs, ABSORICA LD offers a Copay Card and the Patient Assistance Program (PAP) to help eligible patients reduce or eliminate their out-of-pocket costs.

Pregnancy and nursing

Can I take ABSORICA LD if I’m pregnant or trying to get pregnant?

The active ingredient in ABSORICA LD is isotretinoin, which can cause birth defects, miscarriages, premature births, and neonatal death. You should not get pregnant or plan to become pregnant:

  • For 1 month before starting ABSORICA LD
  • While taking ABSORICA LD
  • For 1 month after stopping ABSORICA LD

In order to receive your ABSORICA LD prescription, you must agree to not get pregnant and enroll in the iPLEDGE® Program. If you get pregnant while taking ABSORICA LD, stop taking it right away and call your dermatologist.

Can I breastfeed while taking ABSORICA LD?

Due to the potential for serious adverse reactions in nursing infants from isotretinoin, you should not breastfeed while taking ABSORICA LD and for at least 8 days after the last dose of ABSORICA LD.


How do I register with the iPLEDGE® Program?

Your dermatologist will register you in the iPLEDGE® Program and provide you with an ID card that includes a username. After your dermatologist registers you, your password will be mailed to you to access the iPLEDGE® Program online. You should receive your password within 5 to 10 days.

Why do male patients have to enroll in the iPLEDGE® Program?

Because the iPLEDGE® Program is a restricted distribution program, one of the requirements for the iPLEDGE® Program is the reporting and data collection of sales and dispensing of isotretinoin outside of the iPLEDGE® Program. Therefore, the program is required for all patients in order to effectively manage the distribution of isotretinoin product at all times to all patients.

Should I call my pharmacy ahead of time to ensure that they carry ABSORICA LD?

Prior to filling your ABSORICA LD prescription, contact your pharmacy to ensure that they have enough in stock to fill and dispense your prescription. Your pharmacy must fill and dispense the prescription within the prescription window provided by the iPLEDGE® Program each month.

Dosing guidelines

How do I take ABSORICA LD?

Take ABSORICA LD 2 times a day with or without meals, unless your dermatologist tells you otherwise. Swallow your ABSORICA LD capsules whole with a full glass of liquid. Do not chew or suck on the capsules. ABSORICA LD can hurt your esophagus if it is not swallowed whole.

What if I miss a dose?

If you miss a dose of ABSORICA LD, just skip that dose. Do not take 2 doses at the same time. If you take too much ABSORICA LD or overdose, call your dermatologist or poison control center right away.

Why do I have to get blood tests while taking ABSORICA LD?

ABSORICA LD may cause some side effects that can be detected and managed through blood tests. Therefore, your dermatologist will instruct you to receive monthly blood tests prior to receiving your next 30-day supply of ABSORICA LD. Your dermatologist will check your blood for cholesterol issues, liver abnormalities, blood sugar problems, red and white blood cell counts, and to ensure that you are not pregnant.

Storage and travel

How do I store ABSORICA LD?

ABSORICA LD capsules should be stored at room temperature, between 68°F to 77°F (20°C to 25°C), and protected from light.

Can I travel with ABSORICA LD?

Because ABSORICA LD capsules can be stored at room temperature, traveling with your prescription is relatively easy. If you’re traveling by plane, it’s best to keep your ABSORICA LD prescription in a carry-on bag to ensure easier access.

ABSORICA LD™ tips and tricks

Bring the flavor

Staying hydrated is key to helping your pores get rid of toxins and can also help increase blood flow. Try adding a slice of lemon to your water if you want a little flavor boost.

Ready to take the next step toward clearer skin?

We understand that trying to find a treatment that works for you can sometimes be frustrating or confusing. You may be wondering whether your acne is just a few pimples or a more serious condition that may require help from a dermatologist. No matter where you are in your journey, we have tools to help you take the next step.

Could I have a severe type of acne?

Is it time to talk to my dermatologist?

Could I have a severe type of acne?

Answer these questions to help better understand your acne and find a way to move beyond the breakouts.

My acne looks like:

My acne feels:

I’ve tried: (choose all that apply)

When it comes to taking my medication with food:

I would feel more comfortable going places and doing things if I had clearer skin:

Is it time to talk to my dermatologist?

Talking with your dermatologist about ABSORICA LD is the first step toward finding the clearer skin you’ve been looking for. But knowing how to start that conversation isn’t always easy. Select the topics you’d like to discuss below to help you have a productive discussion at your next appointment.

Select the topics you’d like to discuss: (choose all that apply)

How would you describe your acne?

Which of the following treatments have you tried? (choose all that apply)

I want my summary!

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Rise above your persistent severe (nodular) acne